Research suggests the peptide may not have direct angiogenic effects on cell cultures, instead working through indirect tissue-level mechanisms [5]
In summary, CDC42, derived from neural stem cell-derived exosomes, as well as TIGAR, FTO, and IRP2, contribute to PD pathology by regulating iron homeostasis, ferroptosis, fatty acid metabolism, the antioxidant system, and angiogenesis
The absence of serious adverse events, treatment-related withdrawals, IGF-1 elevation, glucose metabolism impairment, or immunogenic responses represents a favorable safety foundation
Both drugs showed significant antitumor activity, with serum asparaginase activity (SAA) 0.1 UI/ml (considered therapeutic) in 95% of patients in both groups after 18 days of treatment and 25 days after treatment